A NO-CODE MULTI-OMICS NGS PLATFORM

Harmonizing NGS Workflow to Scale with Precision

TWINE delivers meaningful insights through a robust, end-to-end platform validated by NGS experts. As a truly hybrid solution, it integrates effortlessly across your local systems and the cloud, while its platform-agnostic design ensures compatibility with data from any sequencer or library type — bringing precision and speed without limitations.

Watch Demo Explore Applications

Platform-agnostic · Illumina · ONT · MGI · PacBio

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A fine blend of deep genomics expertise and advanced informatics designed for scientific research needs & diagnostic accuracy.

End-to-End Solution

Starting right from raw data files to processing multi-species sequencing reads and generating actionable insights, TWINE handles the complete workflow with 99.9% precision and accelerated speed.

Multi-omics Platform

With a strong focus on multi-omics integration, TWINE delivers unmatched accuracy in genomics and transcriptomics, with future readiness for proteomics and metabolomics.

Fast, Accurate & Scalable

Get results quickly without relying on third parties or compromising accuracy. Whether running a small sample group or a large population cohort, TWINE scales to meet your needs.

Multi-sequencer Compatibility

Process raw short or long, single-end or paired-end reads from all leading sequencing platforms, including Illumina, ONT, MGI, and PacBio.

Advanced Tertiary Analysis

Visualize your results as ready-to-publish tables, plots, and graphs with user-controlled parameter flexibility and flexible file export options.

Comprehensive Analysis

Support for multi-omic sequencing data analysis, longitudinal sample monitoring, and trend tracking — all in one unified platform.

See TWINE in Action

Experience the power of automated NGS data processing

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Experience Real-Time Analysis

Watch how TWINE processes NGS data in real-time, delivering comprehensive gene and variant lists with variant calling, annotation, differential gene expression, and downstream pathway analysis in minutes.

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Multi-faceted Research Applications

TWINE adapts to your specific research and clinical needs

GENOMICS

Targeted or Whole Genome Sequencing

Accelerate your research with flexible analysis pipelines and custom workflows for accurate variant calling.

Whole Genome, Whole Exome & Targeted Panel compatibility
Customizable workflows with gold-standard analysis tools
Detects SNVs, Indels, CNVs and other Structural Variants
Cohort-level analysis and comparison
Selection of both GRCh37 and GRCh38 human build references
Integration with public databases for variant prioritization
Export data for downstream analysis

TRANSCRIPTOMICS

Bulk RNA & Multi-RNA Species Sequencing

Carry out expression and gene-regulation studies with multiple RNA analysis pipelines.

Bulk RNA, mRNA, miRNA, lncRNA, scRNA data analysis compatibility
Additional options for RNA variant and RNA fusion analysis
Advanced feature tool to analyse alternative splicing
Customizable workflows with gold-standard analysis tools
Cohort-level, longitudinal analysis and comparison
Multi-species references from UCSC, Gencode, Ensembl (GRCh37 & GRCh38)
Easy export of data for downstream analysis

METAGENOMICS

Microbial, Fungal & Viral Species Sequencing

Process metagenomic data from multiple sample types and sequencing platforms for species detection and quantification.

Supports Shotgun sequencing, Targeted (16S/18S/ITS) & WGS
Species resolution based on Taxonomy and Phylogeny (DNA & RNA)
Report relative microbial abundance within a sample
Detects SNVs and InDels
Monitor antimicrobial drug resistance genes
Suited for large-scale epidemiological studies

Clinical Applications

Wide-spread Diagnostic & Translational Applications

Transform your human clinical data into actionable insights with rapid, accurate variant detection and interpretation for hereditary conditions, oncology panels, and rare disease diagnosis.

ONCOLOGY

Tumor & Therapy Monitoring

Process somatic tumor-normal matched samples and monitor chemotherapeutic treatment effects over time — all within one unified platform. Track variant allele frequencies, detect emerging resistance mutations, and predict treatment response patterns.

IMMUNOLOGY

Immune & Expression Profiling

Track differential gene expression supported by single-cell data. Gain high-resolution insights into immune cell populations, gene regulation dynamics, and expression-level biomarkers relevant to immunological conditions.

RARE & HEREDITARY DISEASE

Genetic Diagnosis & Variant Discovery

Obtain valuable genetic variants for accurate diagnosis of hereditary and rare disease conditions. Automated variant calling and filtering combined with clinical-grade interpretation accelerates the path from sequencing to actionable diagnosis.